RNA polymerase II clusters form in line with surface condensation on regulatory chromatin

Symbolic picture for the article. The link opens the image in a large view.

Reading about donuts, croissants and jalebis makes you hungry? And you wonder how this is related to our research? Our latest publication in collaboration with the Hilbert and Nienhaus lab (both KIT) revealed that clusters of recruited RNA polymerase II  form in line with surface condensation on regulatory chromatin. In this work we combined live and super-resolution microscopy data of zebrafish embryos with theoretical lattice simulations. Thereby clusters of different sizes and morphologies can be discovered. These range from small and round ones to complex structures such as the delicacies mentioned at the beginning. For more details see the publication in Molecular Systems Biology.